Excellent academic and professional writing includs no spelling errors. Any careless spelling errors will communicate a negative image to readers: if the writer is careless with such little things as spelling, then it is quite likely that the writer is careless with “other little things” such as found in your Methods section. Perhaps readers will doubt the accuracy or precise with “big things” too.
Using a spellcheck is always helpful, so set your software for the US dictionary function. Software dictionaries may or may not include all the variations of spelling. To wit:
North American English spelling is more common nowadays in scientific and technical writing than British English spelling. The University of Tokyo generally uses North American English spelling, punctuation, capitalization, and other similar conventions. see 6.5
Here is a list of some of the important differences in science:
|British system||(North) American System|